Insulin Lyspro which is available as HumalogR, was the first insulin 'analog'. This is a man-made insulin which is different in structure to human insulin. To make this insulin scientists switched the order of two amino acids in human insulin - Lysine and Proline.
Insulin Lyspro is absorbed faster and therefore acts more quickly than soluble insulin. As it works faster, Humalog may cause a more rapid onset of hypoglycaemia. Lyspro lowers blood sugar the most, one hour after it is injected. Its action is usually over by three hours.
Soluble insulin (e.g. human Actrapid, Humulin S) needs to be taken at least 30 minutes before a meal. lyspro/Humalog should be taken either at meal time or no more than 5-15 minutes before a meal.
It is usually taken 3 times a day before meals.
It starts working within 15 minutes. It works best between1-3 hours and lasts from 3-6 hours.
People leading active lives needing soluble insulin as part of a twice daily dosing schedule or basal bolus regimen
.. to be supplied
Cartridges HumalogR 3ml Cartridges to fit a Humapen.
Disposable pens - HumalogR 3ml pre-filled pen
Dr. Nishan Wijenaike, Consultant Physician
West Suffolk Hospitals Diabetes Service